(394) Evaluating Heart Transplant Outcomes Utilizing the Sherpapak Heart Storage System

PurposeMitigating cold ischemic myocardial injury during organ transport may increase cardiac function and improve patient outcomes post-transplant. SherpaPak (SP) is a storage transportation device that maintains the donor heart at constant, hypothermic temperature lower risk of when compared to traditional on ice.MethodsWe retrospectively analyzed adult patients who underwent isolated transplantation University Kansas Medical Center from June 2020 2022. Baseline characteristics were between utilized SP ice. Outcomes groups using Wilcoxon tests for continuous, non-normal variables Fisher's exact or chi-square tests, as appropriate, categorical variables. Multivariable linear regression was used analyze association length stay with clinical predictors.ResultsA total 85 included in study, 25 (29.4%) hearts transported 60 (70.6%) No significant differences noted baseline groups. The group trended towards having higher average age (32 yrs vs. 28 yrs; p = 0.052), time (197 min 177 min; 0.193), bypass (136 127 0.194). Average vasopressin dose (56 units 146 units; 0.034). On multivariable analysis, use associated reduced (11 days vs 19 days; 0.006) after controlling age, time, dose, cause cardiomyopathy, UNOS status transplant, gender matching. difference 30 transplant rejection, readmission mortality groups.ConclusionDespite older longer times, usage shorter post-transplant standard storage. Mitigating We predictors. A Despite